Description
Data Sheet
| Description | Human CRP produced in Human plasma having a molecular mass of 114 kDa. It can be used as a marker for inflammation and also used for monitoring and prediction of future events in coronary artery disease. |
| Expression host | Human Plasma. |
| Formulation | The protein solution is in 20mM TRIS buffer pH 8.0 containing 0.28M NaCl, 0.09% NaN3 and 5mM CaCl2. |
| Protein Background | CRP is an acute phase protein that correlates with inflammatory disease and is synthesized by hepatocytes during the acute phase response by certain cytokines (IL-1 and TNF Alpha and Beta). CRP levels increase dramatically ( up to 1,000 fold) and serve as a useful marker of inflammation in such conditions as bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels. |
| Purity | Greater than 96.0%. |
| Reagent Appearance | Sterile Filtered clear solution. |
| References | Title: Elevation of Intact and Proteolytic Fragments of Acute Phase Proteins Constitutes the Earliest Systemic Antiviral Response in HIV-1 InfectionPublication: PLoS pathogens 6.5 (2010): e1000893.Link: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1000893#ppat-1000893-g006 |
| Stability | Human CRP should be stored at 2-8°C. Do not freeze! |
| Synonyms | C-reactive protein, CRP, PTX1, MGC88244, MGC149895. |
