Description
Cynomolgus CD200R is a member of the CD200R family.The CD200R family consists of one inhibitory member, CD200R and various numbers of activating genes.CD200 (OX2) is a broadly distributed cell surface glycoprotein that interacts with a structurally related receptor (CD200R) and is involved in regulation of macrophage function. CD200R is expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells. CD200R limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. CD200R also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Data Sheet
| Application | For quantitative determination of Cynomolgus CD200R. |
| Assay principle | This assay is a sandwich Enzyme Linked-Immuno-Sorbent Assay (ELISA). |
| Assay Range | 62.5 – 4000 pg/ml |
| Expiration | Six months at 2 – 8 ⁰C. |
| Sample type | Culture Supernates, Serum, plasma, body fluids, tissue lysates. |
| Sensitivity | 30 pg/ml. |
| Size | 96T. |
| Storage | Store at 2 – 8⁰C. Keep Standard and detection antibody at -20⁰C. |
