Description
Data Sheet
| Alternative Name of Analyte | AMPK；AMPKa1；PRKAA1；AMPK |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 562-36000pg/ml |
| Background | 5′-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene.The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 54 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Human/Mouse/Rat Total AMPK alpha 1, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
