Description
Data Sheet
| Alternative Name of Analyte | Hyk；Tie2；tie-2；Cd202b；AA517024 |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 281-18000pg/ml |
| Background | The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations；he TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
| Sensitivity | 27 pg/ml |
| Specificity | reactive with Human Total Tie-2, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
