Description
Data Sheet
| Alternative Name of Analyte | CD140a；Pdgfr-2；AI115593 PDGFRA；CD140A；PDGFR-2；PDGFR2；RHEPDGFRA |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 281-18000pg/ml |
| Background | Alpha-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRA gene.This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 27 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Human Total PDGF R alpha, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
