Description
Data Sheet
| Alternative Name of Analyte | IGF1R；CD221；IGFIR；IGFR；JTK13 |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 140-9000pg/ml |
| Background | The Insulin-like Growth Factor 1 (IGF-1) Receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called Insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults – meaning that it can induce hypertrophy of skeletal muscle and other target tissues. Mice lacking the IGF-1 receptor die late in development, and show a dramatic reduction in body mass, testifying to the strong growth-promoting effect of this receptor. Mice carrying only one functional copy of igf1r are normal, but exhibit a ~15% decrease in body mass. |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 13.5 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Human Total IGF-I R, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
