Description
Related Products
Human ApoA1 ELISA Human ApoB ELISA Human Copeptin ELISA
Human CK-MB ELISA Human D-Dimer ELISA Human FABP3 ELISA
Human Galectin-3 ELISA Mouse Galectin-3 ELISA
Human GDF-15 ELISA Human PAF-AH/Lp-PLA2 ELISA
Human Myeloperoxidase (MPO) ELISA Human Myoglobin ELISA
Human NT-proBNP ELISA Canine NT-proBNP ELISA
Human ST2/IL1RL1 ELISA Human Troponin I ELISA
Data Sheet
| Alternative Name of Analyte | FABP3, FABP11, H-FABP, M-FABP, MDGI, O-FABP, Heart-type fatty acid binding protein, fatty acid binding protein 3 |
| Assay Range | 0.312-20 ng/ml |
| Assay Time | 4.5 hours |
| Assay Type | Sandwich ELISA |
| Background | Fatty acid-binding proteins (FABP) are a family of lipid chaperones involved in the transport and metabolism of fatty acids. So far, at least nine members of the family have been identified. FABPs are 14–15 kDa proteins that reversibly bind hydrophobic ligands, such as fatty acids, with high affinity. Heart-type FABP (H-FABP, also known as FABP3) is a cytosolic, low-molecular-weight protein present in abundance in the myocardium, but also in small quantities in the brain, kidney and skeletal muscle. In the case of acute myocardial infarction (AMI), FABP3 is released from the porous cell membranes of ischemic myocardial cells into circulation due to its small size. Therefore, FABP3 is used as a biochemical marker in the early diagnosis of AMI and acute coronary syndrome, and can provide even better sensitivity than other commonly used markers including cTnI, CK-MB, and myglobin 0–6 hours after the onset of chest pain. However, the concentration of FABP3 is affected by age and renal condition. Also, special attention needs to be addressed to additional analytical issues, such as optimum cut-off value. |
| Dilution Factors | undiluted for serum, plasma |
| Kit Type | Colorimetric |
| Sample Type | Serum, plasma, supernatant, cell or tissue lysate. |
| Sensitivity | 0.16 ng/ml |
| Specificity | Native and recombinant FABP3/H-FABP |
| Storage | 2 – 8 ℃ |
