Description
Background
Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD (NFL), 125 kD (NFM), and 200 kD (NFH) on SDS-gel electrophoresis. Genomic clones for the largest human neurofilament protein (NF-H) were isolated, the intron/exon boundaries mapped and the entire protein-coding regions (exons) sequenced. mutations in neurofilaments have been linked to some forms of Charcot-Marie-Tooth disease (CMT).
Data Sheet
| Application | Cross ReactivityHuman, mouse, rat. |
| Clone | NF-200 |
| Cross Reactivity | Human, mouse, rat. |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen/Antigen | C-terminal segment of enzymatically dephosphorylated pig |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one |
