Description
Background
Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.
Data Sheet
| Application | Cross ReactivityHuman, rabbit, bovine. |
| Clone | GEL-42 |
| Cross Reactivity | Human, rabbit, bovine. |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen/Antigen | Human plasma gelsolin. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
