Description
Background
Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. HSP60 is a self-molecule, it can downregulate adaptive immune responses by upregulating Tregs innately through TLR2 signaling.
Data Sheet
| Application | Cross ReactivityHuman, chicken, rat. |
| Clone | SJ-60 |
| Cross Reactivity | Human, chicken, rat. |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen/Antigen | Recombinant human heat shock protein 60 (HSP60). |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
