Description
IGF1, IGFI, IGF-I, IGF-IA, Mechano growth factor, MGF, Somatomedin C
Data Sheet
| Applications | Direct ELISA, Western Blot, Immuneprecipitation. |
| Clone | NYRhIGF1 |
| Ig Subclass | Mouse IgM |
| Immunogen | r.Human Growth Hormone |
| Protein Background | The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed ‘sulfation factor,’ which later became known as ‘somatomedin’ (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003). |
| Purification Method | Boric acid precipitation |
| Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Synonyms | Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF. |
| Type | Mouse Anti Human Monoclonal. |
