Description
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Background: |
C1 is a non-covalent complex of three different proteins (C1q, C1r and C1s) bound together in a calcium-dependent complex.C1 binds and is activated by antibodies bound to antigens yielding a protease that initiates the classical pathway of complement. |
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Storage: |
-70℃ or below. Avoid freeze/thaw. |
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Source: |
Normal human serum |
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Purity: |
Purified C1 complex is free of other complement proteins, but it contains other high MW plasma proteins. |
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Molecular Weight: |
766,000 Da |
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Size: |
200 µg/vial |
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Concentration: |
>0.20 mg C1/mL based on functional activity measurement |
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Protein Conc. |
0.5 to 5.0 mg/mL total protein |
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Form: |
Frozen liquid |
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Activity: |
more than 250,000 C1H50 units/mg total protein. |
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Buffer: |
10 mM EDTA, 300 mM NaCl, 40% glycerol, pH 5.5, 50 mM sodium acetate, 50 mM EACA, 10 mM benzamidine. |
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Preservative: |
None, 0.22 µm filtered. |
