Description
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Background: |
C3c is derived from iC3b (inactivated C3b) by proteolytic cleavage. iC3b is created by cleavage of C3b by factor I in the presence of factor H, CR1 or MCP. C3c can be produced by an additional cleavage by factor I if the iC3b is bound to CR1. Factor H cannot serve as a cofactor for this cleavage. C3c can also be produced by the action of trypsin-like proteases on iC3b. |
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Storage: |
-70℃ or below. Avoid freeze/thaw. |
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Source: |
Normal human serum |
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Physical Appearance: |
Frozen liquid |
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Purity: |
>90% by SDS-PAGE |
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Molecular Weight: Size: |
139,000 Da (3 chains) 250 µg/vial |
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Concentration: |
1.0 mg/ml |
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Buffer: |
10 mM Sodium phosphate, 145 mM NaCl, pH 7.2 |
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Preservative: |
None, 0.22 µm filtered |
