Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| tumor necrosis factor (ligand) superfamily, member 10 | Polyclonal | IgG | Rabbit | Human | WB | Immunogen affinity purified. |
Immunogen |
||||||
| E.coli-derived human TRAIL recombinant protein (Position: W78-G281). Human TRAIL shares 68% amino acid (aa) sequence identity with mouse TRAIL. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
TNFSF10 |
Protein |
Tumor necrosis factor ligand superfamily member 10 |
Uniprot ID |
P50591 |
Function |
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. |
Tissue Specificity |
Widespread; most predominant in spleen, lung and prostate. |
Sub-cellular localization |
Membrane ; Single-pass type II membrane protein . |
Sequence Similarities |
Belongs to the tumor necrosis factor family. |
Aliases |
Apo 2 ligand antibody|Apo 2L antibody|Apo-2 ligand antibody|Apo-2L antibody|APO2L antibody|CD 253 antibody|CD253 antibody|CD253 antigen antibody|Chemokine tumor necrosis factor ligand superfamily member 10 antibody|Protein TRAIL antibody|TL 2 antibody|TL2 antibody|TNF Related Apoptosis Inducing Ligand antibody|TNF related apoptosis inducing ligand TRAIL antibody|TNF-related apoptosis-inducing ligand antibody|TNF10_HUMAN antibody|TNFSF 10 antibody|TNFSF10 antibody|TNFSF10 protein antibody|TRAIL antibody|TRAIL PEN antibody|Tumor necrosis factor (ligand) family member 10antibody|Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody|Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody|Tumor necrosis factor ligand superfamily member 10 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio’s ECL kit |
AssaySolution recommends Mouse Chemiluminescent WB Detection Kit (AKIT003B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-TRAIL antibody, ASA-B1909–1.jpg
All lanes: Anti-TRAIL(ASA-B1909) at 0.5ug/ml
WB: Recombinant Human TRAIL Protein 0.5ng
Predicted bind size: 42KD
Observed bind size: 42KD
All lanes: Anti-TRAIL(ASA-B1909) at 0.5ug/ml
WB: Recombinant Human TRAIL Protein 0.5ng
Predicted bind size: 42KD
Observed bind size: 42KD
