Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| plasminogen activator, urokinase receptor | Polyclonal | IgG | Rabbit | Human | IHC-P, WB | Immunogen affinity purified. |
Immunogen |
||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human uPA Receptor(293-304aa CNHPDLDVQYRS). | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
PLAUR |
Protein |
Urokinase plasminogen activator surface receptor(U-PAR/uPAR) |
Uniprot ID |
Q03405 |
Function |
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
Tissue Specificity |
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
Sub-cellular localization |
Cell membrane. |
Sequence Similarities |
Contains 3 UPAR/Ly6 domains. |
Aliases |
CD 87 antibody|CD87 antibody|CD87 antigen antibody|MO 3 antibody|MO3 antibody|Monocyte activation antigen Mo3 antibody|Plasminogen activator urokinase receptor antibody|PLAUR antibody|U PAR antibody|u plasminogen activator receptor antibody|U-PAR antibody|UPA receptor antibody|UPAR antibody|UPAR_HUMAN antibody|Urinary plasminogen activator receptor antibody|URKR antibody|Urokinase plasminogen activator receptor antibody|Urokinase plasminogen activator surface receptor antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio’s ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human | AssaySolutio’s IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-uPA Receptor antibody, ASA-B1954, Western blotting
Lane 1: MCF-7 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: SMMC Cell Lysate
Lane 1: MCF-7 Cell Lysate
Lane 2: HELA Cell Lysate
Lane 3: RAJI Cell Lysate
Lane 4: SMMC Cell Lysate
Anti-uPA Receptor antibody, ASA-B1954, IHC(P)
IHC(P): Human Mammary Cancer Tissue
IHC(P): Human Mammary Cancer Tissue
