Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| serpin peptidase inhibitor, clade C(antithrombin), member 1 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen |
||||||
| A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III(93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
SERPINC1 |
Protein |
Antithrombin-III |
Uniprot ID |
P01008 |
Function |
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. |
Tissue Specificity |
Found in plasma. |
Sub-cellular localization |
Secreted, extracellular space. |
Sequence Similarities |
Belongs to the serpin family. |
Aliases |
ANT3_HUMAN antibody|Antithrombin antibody|Antithrombin III antibody|Antithrombin-III antibody|AntithrombinIII antibody|AT 3 antibody|AT III antibody|AT3 antibody|AT3D antibody|ATIII antibody|MGC22579 antibody|Serine(or cysteine) proteinase inhibitor clade C(antithrombin) member 1 antibody|Serine cysteine proteinase inhibitor clade C member 1 antibody|Serine proteinase inhibitor clade C member 1 antibody|SERPIN C1 antibody|Serpin peptidase inhibitor clade C(antithrombin) member 1 antibody|SERPINC1 antibody|THPH7 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Rat Mouse | AssaySolutio’s ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-Antithrombin III antibody, ASA-B0106, Western blotting
Lane 1: Rat Testis Tissue Lysate
Lane 2: SMMC Cell Lysate
Lane 3: JURKAT Cell Lysate
Lane 4: RAJI Cell Lysate
Lane 1: Rat Testis Tissue Lysate
Lane 2: SMMC Cell Lysate
Lane 3: JURKAT Cell Lysate
Lane 4: RAJI Cell Lysate
