Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| toll-like receptor 8 | Polyclonal | IgG | Rabbit | Human, Rat | WB | Immunogen affinity purified. |
Immunogen |
||||||
| A synthetic peptide corresponding to a sequence at the C-terminus of human TLR8 (881-907aa DAYISYDTKDASVTDWVINELRYHLEE), identical to the related mouse sequence. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
TLR8 |
Protein |
Toll-like receptor 8 |
Uniprot ID |
Q9NR97 |
Function |
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Tissue Specificity |
Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells. |
Sub-cellular localization |
Membrane ; Single-pass type I membrane protein . |
Sequence Similarities |
Belongs to the Toll-like receptor family. |
Aliases |
CD 288 antibody|CD288 antibody|CD288 antigen antibody|MGC119599 antibody| MGC119600 antibody|TLR 8 antibody|Tlr8 antibody|TLR8_HUMAN antibody|Toll Like Receptor 8 antibody| Toll-like receptor 8 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Rat | AssaySolutio’s ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- TLR8 antibody, ASA-B1879, Western blotting
All lanes: Anti TLR8 (ASA-B1879) at 0.5ug/ml
Lane 1: Rat Liver Tissue Lysate at 50ug
Lane 2: HEPG2 Whole Cell Lysate at 40ug
Predicted bind size: 120KD
Observed bind size: 120KD
All lanes: Anti TLR8 (ASA-B1879) at 0.5ug/ml
Lane 1: Rat Liver Tissue Lysate at 50ug
Lane 2: HEPG2 Whole Cell Lysate at 40ug
Predicted bind size: 120KD
Observed bind size: 120KD
