Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| ADAM metallopeptidase domain 19 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | IHC-P, WB | Immunogen affinity purified. |
Immunogen |
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| A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19(286-298aa RRKLLAQKYHDNA), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
ADAM19 |
Protein |
Disintegrin and metalloproteinase domain-containing protein 19 |
Uniprot ID |
Q9H013 |
Function |
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). |
Tissue Specificity |
Expressed in many normal organ tissues and several cancer cell lines. |
Sub-cellular localization |
Membrane; Single-pass type I membrane protein. |
Sequence Similarities |
Contains 1 disintegrin domain. |
Aliases |
A disintegrin and metalloproteinase domain 19(meltrin beta) antibody|A disintegrin and metalloproteinase domain 19 antibody|ADAM 19 antibody|ADAM metallopeptidase domain 19 antibody|Disintegrin and metalloproteinase domain containing protein 19 antibody|FKSG 34 antibody|FKSG34 antibody|MADDAM antibody|Meltrin beta antibody|Metalloprotease and disintegrin dentritic antigen marker antibody|MLTN B antibody|MLTNB antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Rat Mouse | AssaySolutio’s ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human, Rat Mouse | AssaySolutio’s IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-ADAM19 antibody, ASA-B0034, Western blotting
Lane 1: Rat Spleen Tissue Lysate
Lane 2: Rat Intestine Tissue Lysate
Lane 3: Rat Brain Tissue Lysate
Lane 4: HELA Cell Lysate
Lane 1: Rat Spleen Tissue Lysate
Lane 2: Rat Intestine Tissue Lysate
Lane 3: Rat Brain Tissue Lysate
Lane 4: HELA Cell Lysate
Anti-ADAM19 antibody, ASA-B0034, IHC(P)
Rat Spleen Tissue
Rat Spleen Tissue
Anti-ADAM19 antibody, ASA-B0034, IHC(P)
Human Lung Cancer Tissue
Human Lung Cancer Tissue
