Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| amyloid beta(A4) precursor-like protein 2 | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | WB | Immunogen affinity purified. |
Immunogen |
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| A synthetic peptide corresponding to a sequence at the C-terminus of human APLP2 (639-656aa, EEKVINSKNKVDENMVID), different from the related rat and mouse sequences by one amino acid. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
APLP2 |
Protein |
Amyloid-like protein 2(APLP-2) |
Uniprot ID |
Q06481 |
Function |
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5′-GTCACATG-3′(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity). |
Tissue Specificity |
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues. |
Sub-cellular localization |
Cell membrane ; Single-pass type I membrane protein . Nucleus . |
Sequence Similarities |
Belongs to the APP family. |
Aliases |
amyloid beta(A4) precursor like protein 2 antibody|Amyloid like protein 2 antibody|Amyloid precursor protein homolog HSD 2 antibody|amyloid precursor protein homolog HSD2 antibody|Amyloid protein homolog antibody|Amyloid-like protein 2 antibody|APLP-2 antibody|Aplp2 antibody|APLP2_HUMAN antibody|APPH antibody|APPL2 antibody|CDEBP antibody|CDEI box binding protein antibody|CDEI box-binding protein antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Rat Mouse | AssaySolutio’s ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-APLP2 antibody, ASA-B0119, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
Lane 3: SMMC Cell Lysate
Lane 1: Rat Brain Tissue Lysate
Lane 2: Rat Heart Tissue Lysate
Lane 3: SMMC Cell Lysate
