Description
Data Sheet
| Description | Bcl-6 Human Recombinant (aa 1-150) expressed in E.coli, shows a 43kDa band on SDS-PAGE (Including GST tag).The Bcl-6 is purified by proprietary chromatographic techniques. |
| Expression host | Escherichia Coli. |
| Formulation | Bcl-6 protein in 50mM Tris-HCl, pH7.5 and 10mM L-glutathione (reduced). |
| Protein Background | Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkins lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitts lymphomas and in nodular, lymphocyte predominant Hodgkins disease. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
| Synonyms | B-cell lymphoma 6 protein, BCL-6, Zinc finger protein 51, LAZ-3 protein, BCL-5, Zinc finger and BTB domain-containing protein 27, BCL6, BCL5, LAZ3, ZBTB27, ZNF51, BCL6A. |
