Description
Overview
Long Name
|
Antibody Type
|
Antibody Isotype
|
Host
|
Species Reactivity
|
Validated Applications
|
Purification
|
| protein phosphatase 3, regulatory subunit B, alpha |
Monoclonal |
IgG |
Mouse |
Bovine, Human, Rat |
IHC-P, WB |
Ascites |
Immunogen
|
| Bovine brain calcineurin. |
Properties
Form
|
Liquid |
Size
|
100 µg/vial |
Contents
|
Mouse ascites fluid, 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as preservative. *carrier free antibody available upon request. |
Concentration
|
|
Storage
|
At -20 °C for 12 months, as supplied, at 2-8 °C for one month. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene
|
PPP3R1 |
Protein
|
Calcineurin subunit B type 1 |
Uniprot ID
|
Human(P63098), Mouse(Q63810), Rat(P63100) |
Function
|
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. |
Tissue Specificity
|
|
Sub-cellular localization
|
Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma. Note: Translocates from the cytosol to the sarcolemma in a CIB1- dependent manner during cardiomyocytes hypertrophy. |
Sequence Similarities
|
Belongs to the calcineurin regulatory subunit family. |
Aliases
|
CNA2|CNB|CNB1|CALNB1|Protein phosphatase 2B regulatory subunit 1|Protein phosphatase 3 regulatory subunit B alpha isoform 1 |
Application Details
| Application |
Concentration* |
Species |
Validated Using** |
| Western blot |
0.25-0.5μg/ml |
Human, bovine, rat |
AssaySolutio’s ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) |
0.5-1μg/ml |
Human, bovine, rat |
AssaySolutio’s IHC/ICC Detection kit |
AssaySolution recommends Mouse Chemiluminescent WB Detection Kit (AKIT003B) for Western blot, and Mouse Peroxidase IHC/ICC Detection Kit (AKIT004B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
