Description
Data Sheet
| Antibody Properties | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
| Available Conjugates | Staining, immunohistochemistry. For staining, use 10ul/1,000,000 cells. Titer for IH should be determined by the investigator. |
| Clone | mCD11a. |
| Ig Subclass | Rat IgG2b. |
| Immunogen | Enriched mouse peritoneal macrophages. |
| Immunological function | This antibody is also available conjugated to biotin and FITC. |
| Protein Background | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. |
| Purification Method | Ion exchange column. |
| Reconstitution | 1mg/ml in PBS (after reconstitution). |
| Storage Procedures | Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |
| Synonyms | Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1ATypeRat Anti Mouse Monoclonal. |
