Description
Data Sheet
| Clone | hCD4. |
| Ig Subclass | Mouse IgG1. |
| Immunogen | Purified human B Cells. |
| Protein Background | CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells. |
| Purification Method | Ion exchange column. |
| Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Synonyms | Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein. |
| Type | Mouse Anti Human Monoclonal. |
