Description
Data Sheet
| Description | Human C4c produced in Human plasma having a molecular mass of 210 kDa. |
| Expression host | Human Plasma. |
| Formulation | The Human Complement C4c solution is in Sodium Phosphate buffer pH 7.0 containing 0.15M NaCl and 0.09% NaN3. |
| Protein Background | Complement C4c is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c.Complement C4c interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes. |
| Purity | Greater than 99.0%. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | Human C4c although stable at 4°C for 1 week, should be stored at -15°C.Please avoid freeze-thaw cycles. |
| Synonyms | Complement C4c, Complement Component C4c, C4c. |
