Description
Please send vector information request to info@novateinbio.com
Data Sheet
| Application | The dCas9 fusion complex is directed to the transcriptional start site (TSS) region of a target gene by pairing between the associated single guide RNA (sgRNA) and the target locus to regulate gene expression. |
| Background | The CRISPR-Cas9 has been repurposed for precise transcriptional regulation of target genes by fusing catalytically disabled Cas9 (dCas9) to transcriptional modulators . |
| Features | pCMV-VPR-dCas9 for gene activation; pCMV-Krab-dCas9 for gene repression. 10 μg each. |
