Description
Data Sheet
| Description | Cytokeratin 8 Human Recombinant full length protein expressed in E.coli, shows a 78 kDa SDS-PAGE.The Cytokeratin 8 is fused to GST-Tag and purified by proprietary chromatographic techniques. |
| Expression host | Escherichia Coli. |
| Formulation | Cytokeratin-8 in 50mM Tris-HCl pH-7.5, 10mM L-glutathione (reduced). |
| Protein Background | Cytokeratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Cytokeratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18. |
| Reagent Appearance | Sterile Filtered clear solution. |
| Stability | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
| Synonyms | Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2. |
