Description
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Background: |
C3d is derived from human C3 after a series of proteolytic cleavages. Surface-bound C3d and its precursors C3dg and iC3b are recognized by complement receptor 2 (CR2, CD21) present on mature B cells and follicular dendritic cells which use these ligands to stimulate phagocytosis and antigen presentation to cells of the adaptive immune system. |
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Storage: |
-70℃ or below. Avoid freeze/thaw. |
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Source: |
Normal human serum |
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Purity: |
>95% by SDS-PAGE |
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Molecular Weight: Size: |
33,800 Da (single chain) 100 µg/vial |
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Concentration: |
1.0 mg/ml |
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Buffer: |
10 mM Sodium phosphate, 145 mM NaCl, pH 7.3 |
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Preservative: |
None, 0.22 µm filtered |
