Description
Human Platelet Activating Factor Acetylhydrolase ELISA Kit
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Different lot may vary, please follow the instruction coming with the kit.
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Data Sheet
| Alternative Name of Analyte | LDL-PLA2; lipoprotein-associated phospholipase A2; LpPLA2; Lp-PLA2; PAF acetylhydrolase; PAF-AH; PAFAHPAF 2-acylhydrolase; phospholipase A2, group VII (platelet-activating factor acetylhydrolase; PLA2G7 |
| Assay Range | 0.156 ng/ml – 10 ng/ml |
| Assay Time | 4.5 hours |
| Assay Type | Sandwich assays |
| Clinical indications | Lp-PLA2 is involved in the development of atherosclerosis, an observation that has prompted interest as a possible therapeutic target (see, e.g. the investigational drug Darapladib). In human atherosclerotic lesions, 2 main sources of Lp-PLA2 can be identified, including that which is brought into the intima bound to LDL (from the circulation), and that which is synthesized de novo by plaque inflammatory cells (macrophages, T cells, mast cells).” It is used as a marker for cardiac disease. A meta-analysis involving a total of 79,036 participants in 32 prospective studies found that Lp-PLA2 levels are positively correlated with increased risk of developing coronary heart disease and stroke. |
| Dilution Factors | 1 to 20 |
| Gene ID | 7941 |
| Kit Type | Colorimetric |
| Sample Type | Serum or plasma |
| Sample Volume | 5 – 10 μL |
| Sensitivity | 0.078 n/ml |
| Specificity | Only detect native and recombinant PAF-AH/Lp-PLA2 |
| Storage | 2 – 8 ℃ |
