Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| insulin-like growth factor 1(somatomedin C) | Polyclonal | IgG | Rabbit | Human, Mouse, Rat | IHC-P, WB | Immunogen affinity purified. |
Immunogen |
||||||
| A synthetic peptide corresponding to a sequence in the middle region of human IGF1(80-96 aa GSSSRRAPQTGIVDECC), different from the mouse and rat sequences by one amino acid. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
IGF1 |
Protein |
Insulin-like growth factor I(IGF-I) |
Uniprot ID |
P05019 |
Function |
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. |
Tissue Specificity |
|
Sub-cellular localization |
Secreted. |
Sequence Similarities |
Belongs to the insulin family. |
Aliases |
IBP1 antibody|IGF 1 antibody|IGF I antibody|IGF IA antibody|IGF IB antibody|IGF-I antibody|Igf1 antibody|IGF1_HUMAN antibody|IGFI antibody|IGFIA antibody|Insulin like growth factor 1(somatomedin C) antibody|Insulin like growth factor 1 antibody|Insulin like growth factor IA antibody|Insulin like growth factor IB antibody|Insulin-like growth factor I antibody|Mechano growth factor antibody|MGF antibody|OTTHUMP00000195080 antibody|OTTHUMP00000195081 antibody|OTTHUMP00000195082 antibody|OTTHUMP00000195083 antibody|OTTHUMP00000195084 antibody|Somatomedia C antibody|Somatomedin C antibody|Somatomedin-C antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human | AssaySolutio’s ECL kit |
| Immunohistochemistry(Paraffin-embedded Section) | 0.5-1μg/ml | Human, Rat Mouse | AssaySolutio’s IHC/ICC Detection kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot, and Rabbit Peroxidase IHC/ICC Detection Kit (AKIT002B) for IHC(P). *Blocking peptide can be purchased at $65. Contact us for more information
Anti-IGF1 antibody, ASA-B0971, Western blotting
WB: Recombinant Human IGF-1 Protein 2.5ng
WB: Recombinant Human IGF-1 Protein 2.5ng
Anti-IGF1 antibody, ASA-B0971, IHC(P)
IHC(P): Human Mammary Cancer Tissue
IHC(P): Human Mammary Cancer Tissue
