Description
Data Sheet
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry, blocking T cell poroliferation. |
| Clone | YNRhIL2. |
| Ig Subclass | Mouse IgG2a. |
| Immunogen | r.Human IL-2. |
| Protein Background | IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
| Purification Method | Ion Exchange. |
| Storage Procedures | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Synonyms | T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2. |
| Type | Mouse Anti Human Monoclonal. |
