Description
Data Sheet
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, Immunohistochemistry, Intracellular staining. |
| Clone | NYRhIL7. |
| Ig Subclass | Mouse IgG1. |
| Immunogen | r.Human IL-7. |
| Protein Background | IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. |
| Purification Method | Ion exchange. |
| Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. |
| Synonyms | Lymphopoietin 1 (LP-1), pre-B cell factor, IL-7TypeMouse Anti Human Monoclonal. |
