Description
Overview
Long Name |
Antibody Type |
Antibody Isotype |
Host |
Species Reactivity |
Validated Applications |
Purification |
| potassium voltage-gated channel, Shal-related subfamily, member 1 | Polyclonal | IgG | Rabbit | Human, Mouse | WB | Immunogen affinity purified. |
Immunogen |
||||||
| E.coli-derived human KCND1 recombinant protein (Position: T442-L647). Human KCND1 shares 90% amino acid (aa) sequence identity with mouse KCND1. | ||||||
Properties
Form |
Lyophilized |
Size |
100 µg/vial |
Contents |
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration |
Reconstitute with 0.2 mL sterile dH2O (500 µg/ml final concentration). |
Storage |
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene |
KCND1 |
Protein |
Potassium voltage-gated channel subfamily D member 1 |
Uniprot ID |
Q9NSA2 |
Function |
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. |
Tissue Specificity |
Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain. |
Sub-cellular localization |
Membrane; Multi-pass membrane protein. Cell projection, dendrite . |
Sequence Similarities |
|
Aliases |
Kcnd1 antibody|KCND1_HUMAN antibody|Kv4.1 antibody|mShal antibody|OTTHUMP00000025805 antibody|OTTHUMP00000025806 antibody|Potassium voltage gated channel Shal related subfamily member 1 antibody|Potassium voltage gated channel subfamily D member 1 antibody|Potassium voltage-gated channel subfamily D member 1 antibody|Shal type potassium channel antibody|Voltage gated potassium channel Kv4.1 antibody|Voltage gated potassium channel subunit Kv4.1 antibody|Voltage-gated potassium channel subunit Kv4.1 antibody |
Application Details
| Application | Concentration* | Species | Validated Using** |
| Western blot | 0.1-0.5μg/ml | Human, Mouse | AssaySolutio’s ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti- KCND1 antibody, ASA-B1108, Western blotting
All lanes: Anti KCND1 (ASA-B1108) at 0.5ug/ml
WB: Recombinant Human KCND1 Protein 0.5ng
Predicted bind size: 39KD
Observed bind size: 39KD
All lanes: Anti KCND1 (ASA-B1108) at 0.5ug/ml
WB: Recombinant Human KCND1 Protein 0.5ng
Predicted bind size: 39KD
Observed bind size: 39KD
Anti- KCND1 antibody, ASA-B1108, Western blotting
All lanes: Anti KCND1 (ASA-B1108) at 0.5ug/ml
Lane 1: Mouse Brain Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: COLO320 Whole Cell Lysate at 40ug
Lane 4: A549 Whole Cell Lysate at 40ug
Predicted bind size: 71KD
Observed bind size: 71KD
All lanes: Anti KCND1 (ASA-B1108) at 0.5ug/ml
Lane 1: Mouse Brain Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Lane 3: COLO320 Whole Cell Lysate at 40ug
Lane 4: A549 Whole Cell Lysate at 40ug
Predicted bind size: 71KD
Observed bind size: 71KD
