Description
Background
Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.
Data Sheet
| Application | Cross ReactivityHuman, mouse, rat. |
| Clone | SA-20 |
| Cross Reactivity | Human, mouse, rat. |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen/Antigen | Rabbit skeletal α-actinin |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
