Description
Background
BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.
Data Sheet
| Application | Cross ReactivityHuman, mouse, rat. |
| Clone | BN-1 |
| Cross Reactivity | Human, mouse, rat. |
| Form | lyophilized |
| Ig type | mouse IgG2b |
| Immunogen/Antigen | Recombinant polypeptide containing amino acids 189-398 |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
