Description
Background
CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7( CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.
Data Sheet
| Application | Cross ReactivityHuman. |
| Clone | IMD-26 |
| Cross Reactivity | Human. |
| Form | lyophilized |
| Ig type | mouse IgG2b |
| Immunogen/Antigen | Recombinant human Cdk7 protein. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
