Description
Background
P-Glycoprotein, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro. MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
Data Sheet
| Application | Cross ReactivityHuman. |
| Clone | PG-13 |
| Cross Reactivity | Human. |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen/Antigen | A mixture of human and hamster drug-resistant whole cells |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one |
