Description
Background
Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p.
Data Sheet
| Application | Cross ReactivityHuman, mouse, rat, chicken, frog. |
| Clone | Tal-33 |
| Cross Reactivity | Human, mouse, rat, chicken, frog. |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen/Antigen | Purified chicken gizzard talin. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one |
