Description
Data Sheet
| Alternative Name of Analyte | SHH；HHG1；HLP3；HPE3；MCOPCB5；SMMCI；TPT；TPTPS |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 15.6-1000 pg/ml |
| Background | Sonic hedgehog is a protein that is encoded by the SHH (sonic hedgehog) gene.Sonic hedgehog is one of three proteins in the mammalian signaling pathway family called hedgehog, the others being desert hedgehog (DHH) and Indian hedgehog (IHH). SHH is the best studied ligand of the hedgehog signaling pathway. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain. Sonic hedgehog is the best established example of a morphogen as defined by Lewis Wolpert’s French flag model—a molecule that diffuses to form a concentration gradient and has different effects on the cells of the developing embryo depending on its concentration. SHH remains important in the adult. It controls cell division of adult stem cells and has been implicated in development of some cancers. |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 3.5 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Mouse Sonic Hedgehog, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
