Description
Data Sheet
| Alternative Name of Analyte | TNFRSF13B；CD267；CVID；CVID2；TACI；TNFRSF14B |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 46.87-3000 pg/ml |
| Background | Tumor necrosis factor receptor superfamily member 13B, also known as TNFRSF13B or more commonly as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system.TACI is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. These proteins signal through TACI inducing activation of several transcription factors including NFAT, AP-1, and NF-kappa-B which then modulate cellular activities. Defects in the function of TACI can lead to immune system diseases. |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 4.5 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Mouse TACI, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
