Description
Mouse Vitamin D Binding Protein (Dbp) ELISA Kit
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Different lot may vary, please follow the instruction coming with the kit.
Data Sheet
| Alternate Names | GC, DBP, DBP/GRD3, HEL-S-51, VDBG, VDBP, Gc-MAF, GcMAF, vitamin D binding protein, DBP-maf, VDB, GC vitamin D binding protein |
| Assay Range | 0.312 to 20 ng/mL |
| Assay Time | 4.5 hours |
| Assay Type | Sandwich ELISA |
| Background | Vitamin D-binding protein (DBP), also/originally known as gc-globulin (group-specific component), is a protein that in humans is encoded by the GC gene.Human GC is a glycosylated alpha-globulin, ~58 kDa in size. Its 458 amino acids are coded for by 1690 nucleotides on chromosome 4 (4q11–q13). The primary structure contains 28 cysteine residues forming multiple disulfide bonds. GC contains 3 domains. Domain 1 is composed of 10 alpha helices, domain 2 of 9, and domain 3 of 4.
Vitamin D-binding protein belongs to the albumin gene family, together with human serum albumin and alpha-fetoprotein. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. As Gc protein-derived macrophage activating factor it is a Macrophage Activating Factor (MAF) that has been tested for use as a cancer treatment that would activate macrophages against cancer cells. |
| Gene ID | 14473 |
| Kit Type | Colorimetric |
| Sample Type | serum, cell supernatant |
| Sensitivity | 0.11 ng/mL |
| Specificity | recognize both native and recombinant DBP |
| UniProt ID | P21614 |
