Description
Background
Tumor necrosis factor-alpha (TNFA), also known as TNFR1, is a potent cytokine, elicits a broad spectrum of biologic responses which are mediated by binding to a cell surface receptor. Mouse TNFα shares 95% amino acid sequence homology with rat. There are 2 different proteins that serve as major receptors for TNF-alpha, one associated with myeloid cells and one associated with epithelial cells. TNFR1 maps to 12p13. TNFR1 signaling is also known to activate the transcription factor NF-kappa B and promote survival.
Data Sheet
| Form | lyophilized |
| Ig type | rabbit IgG |
| Immunogen/Antigen | E. coli-derived mouse TNFα recombinant protein (Position: L80-L235). |
| Reconstitution | 0.2ml of distilled water will yield a concentration of 500μg/ml. |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
