Description
Background
PHB (Prohibitin), also known as PHB1, is a protein that in humans is encoded by the PHB gene. The human prohibitin gene family consists of 1 functional PHB gene on 17q21 and 4 processed pseudogenes, each on a different chromosome. The Phbgene has also been described in animals, fungi, plants, and unicellular eukaryotes. Expressed in blood vessels of human white fat, the work suggested the development of targeted drugs for treatment of obese patients. Prohibitins are divided in two classes, termed Type-I and Type-II prohibitins, based on their similarity to yeast PHB1 and PHB2, respectively. Each organism has at least one copy of each type of prohibitin gene. Prohibitins may have multiple functions including: Mitochondrial function and morphology, Transcriptional modulation.
Data Sheet
| Form | lyophilized |
| Ig type | rabbit IgG |
| Immunogen/Antigen | A synthetic peptide corresponding to a sequence at the |
| Reconstitution | 0.2ml of distilled water will yield a concentration of 500μg/ml. |
| Size | 100ug/vial |
| Storage | At -20C for one year. After reconstitution, at 4C for one month. |
