Description
Data Sheet
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MEDTPLVISK QKTEVVCGVP TQVVCTAFSS HILVVVTQFG KMGTLVSLEP SSVASDVSKP VLTTKVLLGQ DEPLIHVFAK NLVAFVSQEA GNRAVLLAVA VKDKSMEGLK ALREVIRVCQ VW. |
| Description | PSMG3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 142 amino acids (1-122 a.a.) and having a molecular mass of 15.2kDa. The PSMG3 is purified by proprietary chromatographic techniques. |
| Expression host | Escherichia Coli. |
| Formulation | The PSMG3 solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0) and 10% Glycerol. |
| Protein Background | PSMG3 is a chaperone protein that promotes assembly of the 20S proteasome. PSMG3 may cooperate with PSMG1-PSMG2 heterodimers to coordinate the correct assembly of proteasomes. PSMG3 interacts with PSMG4, as well as directly with alpha and beta subunits of the 20S proteasome but dissociates prior to the formation of half-proteasomes, probably upon recruitment of POMP. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Quality Control Test | MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGG. |
| Reagent Appearance | Sterile Filtered colorless solution. |
| Stability | PSMG3 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Synonyms | Proteasome assembly chaperone 3, PAC-3, hPAC3, PSMG3, PAC3, C7orf48, MGC10911. |
