Description
Data Sheet
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MKGLYFQQSS TDEEITFVFQ EKEDLPVTED NFVKLQVKAC ALSQINTKLL AEMKMKKDLF PVGREIAGIV LDVGSKVSFF QPDDEVVGIL PLDSEDPGLC EVVRVHEHYL VHKPEKVTWT EAAGSIRDGV RAYTALHYLS HLSPGKSVLI MDGASAFGTI AIQLAHHRGA KVISTACSLE DKQCLERFRP PIARVIDVSN GKVHVAESCL EETGGLGVDI VLDAGVRLYS KDDEPAVKLQ LLPHKHDIIT LLGVGGHWVT TEENLQLDPP DSHCLFLKGA TLAFLNDEVW NLSNVQQGKY LCILKDVMEK LSTGVFRPQL DEPIPLYEAK VSMEAVQKNQ GRKKQVVQF. |
| Description | CRYZL1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 369 amino acids (1-349 a.a.) and having a molecular mass of 40.8 kDa. CRYZL1 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. |
| Expression host | Escherichia Coli. |
| Formulation | CRYZL1 solution containing 20mM Tris-HCl buffer (pH8.0), 2mM DTT, 0.1M NaCl and 20% glycerol. |
| Protein Background | Quinone Oxidoreductase (CRYZL1) is a protein that has sequence similarity to zeta crystalline. CRYZL1 has NADPH-dependent quinone reductase activity distinct from other known quinone reductases, and may have a role as a pH response element-binding protein. CRYZL1 contains an NAD(P)H binding site. CRYZL1 is expressed at different levels in the heart, brain, skeletal muscle, kidney, pancreas, liver and lung. CRYZL1 is present at low levels in human lens tissue. |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Reagent Appearance | Sterile filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Synonyms | Quinone Oxidoreductase-like Protein 1, Quinone oxidoreductase homolog 1, Zeta-crystallin homolog, Protein 4P11, QOH-1, CRYZL1, 4P11. |
