Description
Data Sheet
| Alternative Name of Analyte | IL-1；IL1F2；IL1-BETA |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 62.5-4000 pg/ml |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 6 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Rat IL-1 beta, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
