Description
Data Sheet
| Alternative Name of Analyte | HAVCR1；HAVCR；HAVCR-1；KIM-1；KIM1；TIM；TIM-1；TIM1；TIMD-1；TIMD1 |
| Assay duration | 4 hours |
| Assay format | Sandwich |
| Assay Range | 15.6-1000 pg/ml |
| Background | Hepatitis A virus cellular receptor 1 (HAVcr-1) also known as T-cell membrane protein 1 (TIM-1) is a protein that in humans is encoded by the HAVCR1 gene. The hepatitis A virus cellular receptor 1 (HAVCR1/TIM-1), is a member of the TIM (T cell transmembrane, immunoglobulin, and mucin) gene family, which plays critical roles in regulating immune cell activity especially regarding the host response to viral infection. TIM-1 is also involved in allergic response, asthma, and transplant tolerance.The TIM gene family was first cloned from the mouse model of asthma in 2001.Subsequently it was demonstrated that members of the TIM gene family including TIM-1 participate in host immune response. The mouse TIM gene family contains eight members (TIM-1-8) while only three TIM genes (TIM-1, TIM-3, and TIM-4) have been identified in humans. |
| Sample type | serum, plasma, cell culture supernatant |
| Sensitivity | 3.5 pg/ml |
| Size | 96 Tests |
| Specificity | reactive with Rat TIM-1, reactivity with other related proteins not observed |
| Storage | 2-8℃ |
