Description
Data Sheet
| Amino acid sequence | MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY LEHHHHHH. |
| Description | SOX2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 208 amino acids (1-200 a.a.) and having a molecular mass of 23.1kDa. SOX2 protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography. |
| Expression host | Escherichia Coli. |
| Formulation | The SOX2 solution contains 20mM Tris-HCl pH-8, 2mM DTT, 0.2M NaCl & 40% glycerol. |
| Protein Background | SOX2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX4 is important for early embryogenesis and for embryonic stem cell pluripotency. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Reagent Appearance | Sterile filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Synonyms | MCOPS3, ANOP3, MGC2413, SOX2, SRY (sex determining region Y)-box 2. |
