Description
Data Sheet
| Amino acid sequence | MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVMLDEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG. |
| Description | SNAP25 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids and having a molecular mass of 23 kDa. |
| Expression host | Escherichia Coli. |
| Formulation | The protein solution contains 25mM Tris-HCl pH7.5, 2mM EDTA, 10% glycerol and 1mM DTT. |
| Protein Background | SNAP-25 is an necessary element of the core complex that is responsible for presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters and this protein exists as two alternative isoforms, SNAP25A and SNAP25B which differ by 9 amino acids in central portion of these proteins. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Reagent Appearance | Sterile Filtered colorless solution. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Synonyms | Super-Protein, SUP, RIC4, SEC9, SNAP, RIC-4, SNAP25, SNAP-25, Synaptosomal-associated protein 25, Synaptosomal-associated 25 kDa protein, FLJ23079, bA416N4.2, dJ1068F16.2. |
